HORDB

ID: hor001531
Uniprot ID: Q01133
Protein name: Antho-RFamide
Gene name: NA
Organism: Calliactis parasitica (Sea anemone) (Actinia parasitica)
Family: FARP (FMRFamide related peptide) family
Source: animal
Expression: Neurons associated with smooth muscle fibers.
Disease: NA
Comments: NA
Taxonomy: Calliactis (genus), Hormathiidae (family), Nynantheae (suborder), Actiniaria (order), Hexacorallia (subclass), Anthozoa (class), Cnidaria (phylum), Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Sequence: QGRF
Length: 4
Propeptide: MLVAMTTASYVTILVTLLFHILTINAKTVTKRAKETNLEDDEPQYWRGRFAKDVVPQFWKGRFSDPQFWKGRFSDPQFWKGRFSSHGNKRRYVPGRYGREFQGRFGREFQGRFGREQGRFGREEDQGRFGREEDQGRFGREEQGRFGREEDQGRFGREEDQGRFGREEDQGRFGREEEQGRFGREEDQGRFGREEEQGRFGREEDQGRFGREEDQGRFGREEEQGRFGKRDEDQGRFGKREDQGRFGKRDEDQGRFGKRDEDQGRFGKREDQGRFGKREDQGRFGRELLAKLNKRTTSIQEDPQTRFRDVQMTRRNVAKKDKIEESNDEEANKS
Signal peptide: MLVAMTTASYVTILVTLLFHILTINA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor001531_AF2.pdb

hor001531_ESM.pdb

Mass:	56025	Formula:	C22H34N8O6
Absent amino acids:	ACDEHIKLMNPSTVWY	Common amino acids:	FGQR
pI:	10.55	Basic residues:	1
Polar residues:	1	Hydrophobic residues:	1
Hydrophobicity:	-140	Boman Index:	-1654
Half-Life:	0.8 hour	Half-Life Yeast:	10 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	0
Instability Index:	750	Extinction Coefficient cystines:	0
Absorbance 280nm:	0

PubMed ID: 1706527
Title: Primary structure of the precursor for the sea anemone neuropeptide Antho-RFamide (